Visitor weblog: 3 misconceptions of utilizing injectable antipsychotic remedy for schizophrenia


by Eric Hughes, M.D., Ph.D.

Societal perceptions of schizophrenia are sometimes sensationalized and shrouded in stigmas that may result in misconceptions and the unfold of inaccurate info each exterior and inside the neighborhood. These destructive or false beliefs can come from media, cultural attitudes, and institutional bias (employers, police, and even the medical neighborhood), impacting sufferers’ remedy journeys and doubtlessly maintaining them from optimizing their illness administration.

Amongst sufferers with schizophrenia, caregivers, and well being care suppliers, a standard false impression is that use of long-acting injectable antipsychotics (LAIs) is barely acceptable for extreme instances. Nevertheless, LAIs could also be appropriate for quite a lot of sufferers and even utilized in early remedy to permit for improved adherence – the affected person receiving the medicine as prescribed – and high quality of life. For that reason, they’re sometimes really helpful to sufferers preferring LAIs or who could wrestle to stick to a each day oral routine.

As well as, relapse continues to be an ongoing and sophisticated problem confronted by many schizophrenia sufferers, with charges estimated to be between 50-92% globally. LAIs assist to take care of secure blood ranges and have been proven to scale back the danger of relapse. Regardless of the confirmed effectiveness, LAIs are solely used as first-line remedy choices within the U.S. about 4% of the time.

It’s vital to make clear a number of the different widespread misconceptions of LAIs, together with:

False impression #1: Therapy value is out of attain

A large number of private and non-private insurance coverage might help cowl the price of LAI antipsychotics, and in some instances the drug producer might also present help.

False impression #2: Sufferers choose oral remedy

Within the well being care neighborhood, oral medicine is often the usual first alternative remedy of schizophrenia, particularly for first-episode sufferers, as a result of assumption that sufferers choose it. Nevertheless, there are examples of schizophrenia sufferers and their family members with favorable notion of LAIs. Subsequently, it’s vital for well being care suppliers to supply injectable LAIs as an choice to their sufferers early of their remedy journey, which permits sufferers to debate advantages and dangers of various remedy choices with their medical doctors to search out the one most acceptable for them.

False impression #3: Therapy with LAIs is a punishment

A psychotic episode generally is a traumatic expertise which may be additional compounded by a necessity for hospitalization, which may go away sufferers ambivalent about receiving medicines involuntarily. Traditionally, this has created a destructive notion of injectable therapies, however attitudes could change throughout illness relapse and remission intervals. Immediately’s LAIs provide remedy choices for sufferers and medical doctors which will assist meet the affected person’s wants or preferences.

Elevating consciousness of those misconceptions has the potential to assist sufferers and caregivers think about essentially the most acceptable remedy possibility for them. Ought to any particular person imagine LAIs could also be useful to their remedy journey, they’re inspired to begin a dialog with their physician.

Eric Hughes, M.D., Ph.D., is the manager vp of worldwide analysis and improvement and chief medical officer at Teva Prescribed drugs.

October 2023 


The views and opinions expressed on this weblog solely belong to the writer, and exterior content material doesn’t essentially replicate the views of Psychological Well being America.



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