A world group of researchers led by the Division of Pharmacology and Pharmacy, LKS College of Medication, the College of Hong Kong (HKUMed), and together with Douglas P Kiel, MD, MPH, Director Musculoskeletal Analysis Middle, Marcus Institute for Getting old Analysis, Hebrew SeniorLife, and Professor of Medication, Harvard Medical Faculty, evaluated the secular developments in hip fracture incidence, remedy patterns following a hip fracture, and all-cause mortality in 19 nations and areas from 2005 to 2018.
Whereas the age- and sex-standardized hip fracture incidence charges decreased in most areas, the variety of hip fractures worldwide are projected to almost double by 2050 in comparison with 2018. The examine, not too long ago revealed in Journal of Bone and Mineral Analysis, highlights an pressing want for higher methods in hip fracture prevention and care.
Hip Fracture Statistics
On this worldwide examine, researchers immediately accessed to the information from a big consultant cohort involving 19 nations and areas to look at the incidence of hip fractures, remedy following a hip fracture, and all-cause mortality following hip fractures, amongst sufferers aged 50 years and older, from 2005 to 2018.
Earlier stories on hip fracture incidence have been based mostly on knowledge with heterogeneity in knowledge sources, examine intervals, and analytical approaches. In distinction, this examine utilized a standardised protocol and a typical knowledge mannequin throughout all websites to offer comparable knowledge.
Age- and sex-standardized incidence charges of hip fracture have been estimated utilizing the 2020 United Nations world inhabitants as a normal. The variety of hip fractures in 2030, 2040, and 2050 have been projected based mostly on the developments within the incidence charges and the World Financial institution knowledge. Inside 12 months following hip fractures, the proportion of sufferers receiving anti-osteoporosis treatment, and the all-cause mortality charges have been estimated.
A complete of 4,115,046 hip fracture circumstances have been recognized within the cohort. The reported age- and sex-standardized incidence charges of hip fractures ranged from 95.1 (Brazil) to 315.9 (Denmark) per 100,000 inhabitants. Most nations and areas confirmed a reducing development in hip fracture incidence, with essentially the most pronounced declines in Denmark (‐2.8% per yr), Singapore (‐2.8%), and Hong Kong (‐2.4%). The most important will increase have been famous within the Netherlands (+2.1%), and South Korea (+1.2%). Regardless of the general decline in hip fracture incidence, the whole variety of hip fractures is estimated to almost double from 2018 to 2050.
Inside 1 yr following a hip fracture, post-fracture remedy remained low all through the years, starting from 11.5% in Germany to 50.3% in United Kingdom. One-year all-cause mortality charges ranged from 14.4% (Singapore) to twenty-eight.3% (United Kingdom), whereas mortality developments various from ‐5.3% to +18.4% per yr. Males had decrease use of anti-osteoporosis treatment than females, greater charges of all-cause mortality, and a bigger enhance within the projected variety of hip fractures by 2050.
A key message from the examine is that decline in hip fractures in lots of nations in recent times shouldn’t be sufficient to offset the influence of the growing older inhabitants. The burden of hip fracture is predicted to proceed to develop. Provided that hip fracture shouldn’t be solely a medical concern, but additionally a social concern that always requires institutionalization, authorities coverage and multidisciplinary intervention needs to be thought of to cut back the influence of the hip fracture within the coming 30 years.
- International Epidemiology of Hip Fractures: Secular Developments in Incidence Charge, Publish-Fracture Therapy, and All-Trigger Mortality – (https://asbmr.onlinelibrary.wiley.com/doi/10.1002/jbmr.4821)