Is 3D SVR MRI the Key to Declassifying Fetal Optic Nerve?
In Juang et al.’s retrospective examine, all fetal MRI examinations carried out at Phoenix Youngsters’s Hospital between January 1, 2020 and August 1, 2022 had been reviewed to seek out these with adequate high quality to reconstruct a 3D SVR picture. First, a medical pupil reader examined the unprocessed fetal mind MRIboth from balanced turbo-field-echo or T2-weighted single-shot quick spin echo (T2 SSFSE) sequencestrying FOP measurements the place possible.
Then, 3D SVR reconstructions of fetal mind photos had been carried out utilizing a minimal of six T2 SSFSE imaging sequences. With that very same reader subsequent inspecting the reconstructed imaging and recording FOP measurements, two pediatric neuroradiologists with practically a decade of expertise learn all FOP measurements. And to estimate the connection between FOP measurements of regular fetuses and gestational age, nomograms had been generated accordingly.
Finally, out of 70 fetal MRI scans chosen for this ARRS Annual Assembly Summa Cum Laude award-winning On-line Poster, FOP was visualized in 9 circumstances in unprocessed fetal MRIs, in comparison with 55 circumstances in 3D SVR photos. Moreover, among the many 55 3D SVR circumstances, pre-chiasmatic optic nerve width was efficiently measured bilaterally in 53 circumstances, optic chiasm width in all 56 circumstances, and bilateral optic tract width in 30 circumstances.
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Particularly, a linear regression match estimated the connection between optic chiasm width (OCW) in millimeters in regular fetuses and gestational age (GA) in weeks as OCW = 0.11 × GA+2.0 (R^2 = 0.30); equally, the connection between pre-chiasmatic (PC) optic nerve width and GA was estimated as PC = 0.04 × GA +0.24 (R^2 = 0.34).
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