Easy Letters Promote Higher-informed Opioid Prescribing

To run the trial, the researchers partnered with the Minnesota Board of Pharmacy, which administers the PMP, and Minnesota Administration and Funds Company, which promotes using high-quality proof to enhance state decision-making. They enrolled 12,000 clinicians who prescribed opioids with benzodiazepines or opioids with gabapentinoids. The clinicians had been then randomly assigned to a management group or to obtain considered one of three sorts of letters: mandate letters focusing a brand new state requirement to verify the PMP earlier than prescribing opioids, info letters about their sufferers prescribed opioids with benzodiazepines or gabapentinoids, or mixed letters that included each messages. The letters had been despatched in spring 2021.

Sacarny and co-authors analyzed the results of the letters utilizing de-identified knowledge from the PMP. The information included all opioid, benzodiazepine, and gabapentinoid prescriptions distributed all through Minnesota, in addition to all PMP account data and searches.


The researchers discovered that letters mentioning the mandate to verify the PMP efficiently elevated engagement with this system. PMP search charges rose by 9 p.c, and the impact persevered at the very least 8 months. The letters additionally inspired clinicians to make PMP accounts, a prerequisite for looking out. Results had been related for the mixed letters, which talked about the mandate and in addition included prescribing info.

“The enduring impacts counsel that the letters inspired engagement amongst clinicians who wouldn’t have in any other case created PMP accounts or searched the PMP. This discovering is noteworthy as a result of account creation is a crucial barrier to PMP use,” famous Mireille Jacobson, Ph.D., the research’s final writer and affiliate professor of Gerontology on the College of Southern California.

The researchers notice that different state PMPs or healthcare organizations might simply ship related letters as part of an economical evidence-based technique to advertise safer prescribing. As a result of the mandate letters include no protected well being info, they may be despatched over e-mail, additional reducing the intervention price.

The researchers detected no results of the data letters, which didn’t deal with the brand new mandate to verify the PMP. Not one of the letters led to detectable modifications in prescribing.

“Whereas the letters didn’t make a detectable distinction in prescribing, we nonetheless assume these outcomes are encouraging,” famous Sacarny. “Letters specializing in the mandate efficiently promoted PMP engagement by way of looking out and account-holding, which meant clinicians had higher entry to key affected person knowledge as they selected remedy.”

The research’s co-authors are Tatyana Avilova of the College of Tokyo, David Powell of the RAND Company, Ian Williamson and Weston Merrick of Minnesota Administration and Funds, and Mireille Jacobson of the College of Southern California.

The research was supported by the Abdul Latif Jameel Poverty Motion Lab and the Nationwide Institute for Well being Care Administration.

Supply: Eurekalert


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