Dysphagia Has Emerged as ‘High’ Scientific Symptom Amongst COVID-19 Sufferers

The SARS-CoV-2 an infection has been linked to an estimated 360 million diseases and 5.6 million fatalities for the reason that begin of the COVID-19 pandemic. Whereas vaccine safety in opposition to the SARS-CoV-2 virus has been rising globally, the primary incidence of Omicron—the novel type of concern—has been reported. Since then, Omicron has swiftly unfold over the world, displacing the Delta kind and creating contemporary outbreaks in a number of nations.

“Because the begin of the pandemic, ZOE has constantly documented the commonest COVID signs and the way they’ve modified over time,” based on the ZOE Well being Research, which collects sufferers’ information on their signs.

“These signs have developed on account of quite a lot of elements, together with the introduction of vaccinations and the looks of novel variations.”

“The SARS-CoV-2 coronavirus that causes COVID-19, like all viruses, is consistently creating by way of its potential to transmit and the signs it produces.”


A case collection of COVID-19-positive sufferers who sought therapy on the ENT ED for acute odynophagia, extreme sore throat, and fever was introduced.

Throughout the preliminary weeks of the Omicron wave in Sweden, “we noticed a lot of younger sufferers with this scientific indication of SARS-CoV-2 an infection. COVID-19-associated acute laryngitis and/or pharyngitis occurred in all topics.”

The scientific triad of signs displayed by these sufferers advised that they have been affected by the possibly deadly sickness epiglottitis. In consequence, a immediate scientific examination, together with laryngoscopy, was required to find out a analysis and information the therapy.

“Not one of the people on this trial had a swollen or edematous epiglottis that required airway care. Just one affected person had edema within the arytenoid space.”

“Nevertheless, we discovered seven instances of acute epiglottitis with concurrent COVID-19 an infection within the literature, thus this analysis must be investigated and shortly dominated out, particularly if a affected person presents with a attribute scientific triad,” claimed the ZOE well being examine.

The scientific presentation of SARS-CoV-2 an infection has turn into a standard COVID-19 symptom of the Omicron kind, with acute odynophagia, extreme sore throat, and fever. Signs similar to coughing, fever, and lack of style or odor have been extra prevalent in previous waves. At present, Omicron-infected sufferers hardly ever report these signs.

Preliminary analysis means that Omicron causes milder signs than Delta, though it’s unclear if the decrease severity is attributable to the variant’s options or elevated world vaccination immunity. Despite the fact that preliminary analysis means that Omicron is milder, a substantial variety of sufferers require hospitalization to handle their signs. Within the described cohort, 20% required hospitalization for symptom therapy. All the sufferers had obtained not less than two doses of the COVID-19 vaccine.

The creator of the examine added, “As soon as epiglottitis was dominated out, sufferers within the described cohort got diagnoses similar to acute viral laryngitis or acute viral pharyngitis based mostly on laryngoscopy photos of the larynx and hypopharynx.”

A couple of sufferers with secondary bacterial infections got antibiotics orally. Acute laryngitis is historically handled with voice relaxation, analgesic treatment, and humidification. Based on the findings of a Cochrane evaluate on the advantages of antibiotic therapy for acute laryngitis in adults, antibiotics look like ineffective in treating this situation.

Lastly, we offer a case collection of 20 sufferers who have been dropped at our ENT ED in the course of the SARS-CoV-2 Omicron wave with COVID-19-associated laryngotracheitis and pharyngitis. The commonest signs in these sufferers have been acute odynophagia, a extreme sore throat, and fever.

Nearly all of sufferers have been younger, wholesome, and had obtained the COVID-19 vaccination. This scientific manifestation of COVID-19 was uncommon in earlier waves. As a result of an analogous set of signs is related to the possibly deadly sickness epiglottitis, a fast examination of the larynx is suggested to rule out higher airway inflammatory emphysema.

Not one of the sufferers with COVID-19-related odynophagia had edema within the larynx or epiglottis, leading to airway obstruction. Regardless of being vaccinated in opposition to COVID-19, 20% of the affected person’s required hospitalization for symptom therapy. Within the absence of airway edema, acute odynophagia is handled with high-dose analgesics, NSAIDs, and native anesthetics to numb the mouth and throat lining. In extreme instances, epinephrine inhalation and oral/intravenous corticosteroids could also be required to ease signs.

Reference :

  1. Acute odynophagia: A brand new symptom of COVID-19 in the course of the SARS-CoV-2 Omicron variant wave in Sweden – (https:pubmed.ncbi.nlm.nih.gov/35170099/)

Supply: Medindia


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